We use a set of mobile agents to operate the CFD approach and present a mobile agent-based computation-flow delegation framework (MABCFD) to execute the workflow tasks. The CFD approach lets the tool services of the workflow to dynamically migrate analysis tools towards the datasets to perform computation on data side during workflow execution. Since the size of the analysis tools are much smaller than the datasets size in a workflow, in this paper, to minimize the dataflow and improve workflow performance, we propose a novel computation-flow delegated (CFD) approach. This model of moving data to computation during workflow execution weakens the performance of the workflow especially when the orchestrated bioinformatics workflow has to handle big-data in it. Existing orchestrated bioinformatics workflow execution approaches necessitate the transfer of datasets from biological data services to the analysis tool (computation) services of the workflow for various data analysis.
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